The fastest (O(n)) and most memory efficient (O(1)) way is with the XOR operation.
In C:
int arr[] = {3, 2, 5, 2, 1, 5, 3};
int num = 0, i;
for (i=0; i < 7; i++)
num ^= arr[i];
printf("%i
", num);
This prints "1", which is the only one that occurs once.
This works because the first time you hit a number it marks the num variable with itself, and the second time it unmarks num with itself (more or less). The only one that remains unmarked is your non-duplicate.
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